A Case of Polyostotic Fibrous Dysplasia of the Temporal Bone and Sphenoid Sinus
نویسندگان
چکیده
منابع مشابه
A case of craniofacial polyostotic fibrous dysplasia.
We present the case of a patient with craniofacial polyostotic fibrous dysplasia. Polyostotic fibrous dysplasia is relatively rare and usually presents in late childhood/early adulthood. It is occasionally associated with endocrine disorders such as McCune-Albright syndrome. The benign pathology of this bone tumor belies its implications in the region of the skull base. Craniofacial polyostotic...
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Fibrous dysplasia is a condition leading to abnormal differentiation of osteoblasts which leads to replacement of normal bone with fibrous stroma [1-3]. It may involve single bone (monostotic) or multiple bones (polyostotic). It may affect any bone however; skull and ribs are the commonest [2,4-6]. It is usually asymptomatic and is an incidental finding. It may become symptomatic when complicat...
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BACKGROUND Polyostotic fibrous dysplasia is a skeletal disease that results from somatic activating mutations in the gene GNAS in skeletal stem cells, leading to proliferation of immature osteogenic cells with replacement of normal marrow and bone with fibro-osseous tissue. Lesions may cause bone deformity or fracture. In the surgical care of polyostotic fibrous dysplasia, the role of grafting ...
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An 18-year-old man was referred to the authors' institution's thoracic cancer specialists for further consultation after abnormal findings were seen on chest radiograph.
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ژورنال
عنوان ژورنال: Journal of Clinical Otolaryngology Head and Neck Surgery
سال: 2000
ISSN: 1225-0244,2713-833X
DOI: 10.35420/jcohns.2000.11.2.319